Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046585 | 0.89 | SLC2A2 (0.41) | SLC2A1ALBOPRK1KCNH2TSPO | |
| SCHEMBL4671342 | 0.88 | SLC2A1 (0.41) | SLC2A1MTNR1AMTNR1BALBOPRK1 | |
| SCHEMBL14046533 | 0.85 | MTNR1A (0.39) | SLC2A1MTNR1AMTNR1BTSPOGABRB2 | |
| SCHEMBL4671352 | 0.83 | SLC2A1 (0.48) | SLC2A1MTNR1AMTNR1B | |
| SCHEMBL14046548 | 0.80 | SLC2A1 (0.42) | SLC2A1ALBOPRK1KCNH2TSPO | |
| SCHEMBL8036292 | 0.79 | MCHR1 (0.40) | SLC2A1 | |
| SCHEMBL11934195 | 0.79 | SLC2A1 (0.42) | SLC2A1ALBOPRK1KCNH2TSPO | |
| SCHEMBL14046560 | 0.79 | SLC2A1 (0.50) | SLC2A1 | |
| SCHEMBL11929574 | 0.78 | MC4R (0.47) | SLC2A1 | |
| SCHEMBL4669651 | 0.78 | SLC2A1 (0.40) | SLC2A1ALBOPRK1KCNH2TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116665-A1 | SUBSTITUTED IMIDAZOPYRIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR ANTAGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2008-10-02 | — | — | WO | disclosed |