Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.57 |
| ▸ | ACACA | Q13085 | 2/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.54 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13420207 | 1.00 | ACLY (0.57) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420516 | 1.00 | ACLY (0.57) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420437 | 1.00 | ACLY (0.57) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420408 | 1.00 | ACLY (0.57) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420592 | 1.00 | ACLY (0.57) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420517 | 1.00 | ACLY (0.57) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420204 | 0.91 | ACLY (0.54) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420699 | 0.91 | ACLY (0.54) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420519 | 0.91 | ACLY (0.54) | ACLYACACAHSD11B1HSD11B2NR3C1 | |
| SCHEMBL13420438 | 0.91 | ACLY (0.54) | ACLYACACAHSD11B1HSD11B2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130449-A2 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |