Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.41 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13420380 | 1.00 | GPBAR1 (0.41) | GPBAR1SLC10A1HSD11B1 | |
| SCHEMBL13420644 | 1.00 | GPBAR1 (0.41) | GPBAR1SLC10A1HSD11B1 | |
| SCHEMBL13420373 | 0.88 | HSD11B1 (0.43) | GPBAR1SLC10A1HSD11B1 | |
| SCHEMBL13420797 | 0.88 | HSD11B1 (0.43) | GPBAR1SLC10A1HSD11B1 | |
| SCHEMBL14047197 | 0.88 | HSD11B1 (0.43) | GPBAR1SLC10A1HSD11B1 | |
| SCHEMBL13420651 | 0.88 | HSD11B1 (0.43) | GPBAR1SLC10A1HSD11B1 | |
| SCHEMBL13642452 | 0.86 | GPBAR1 (0.35) | GPBAR1 | |
| SCHEMBL13642516 | 0.86 | GPBAR1 (0.35) | GPBAR1 | |
| SCHEMBL13420650 | 0.83 | HSD11B1 (0.42) | GPBAR1SLC10A1HSD11B1 | |
| SCHEMBL13420371 | 0.83 | HSD11B1 (0.42) | GPBAR1SLC10A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130449-A2 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |