Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15291974 | 0.91 | SMN1; SMN2 (0.40) | SMN1; SMN2HSD17B10GAASTAT3ALDH1A1 | |
| SCHEMBL14092186 | 0.84 | HSD17B10 (0.44) | SMN1; SMN2HSD17B10GAASTAT3ALDH1A1 | |
| SCHEMBL16213017 | 0.82 | STAT3 (0.46) | SMN1; SMN2HSD17B10GAASTAT3ALDH1A1 | |
| SCHEMBL16213013 | 0.82 | STAT3 (0.46) | SMN1; SMN2HSD17B10GAASTAT3ALDH1A1 | |
| SCHEMBL16213015 | 0.82 | STAT3 (0.46) | SMN1; SMN2HSD17B10GAASTAT3ALDH1A1 | |
| SCHEMBL15372144 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2HSD17B10GAASTAT3ALDH1A1 | |
| SCHEMBL750738 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2HSD17B10GAAALDH1A1DHODH | |
| SCHEMBL10203187 | 0.76 | GAA (0.50) | GAAALDH1A1CTSLATML3MBTL1 | |
| SCHEMBL2176311 | 0.75 | GAA (0.45) | SMN1; SMN2GAASTAT3ALDH1A1MEN1 | |
| SCHEMBL25170169 | 0.75 | STAT3 (0.44) | GAASTAT3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130464-A1 | MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME | TRANZYME PHARMA, INC. (US) | 2008-10-30 | — | — | WO | disclosed |