Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211108 | 0.82 | FAAH (0.46) | FAAHCES1 | |
| SCHEMBL10062273 | 0.79 | — | — | |
| SCHEMBL21466607 | 0.79 | — | — | |
| SCHEMBL15249281 | 0.79 | — | — | |
| SCHEMBL8407701 | 0.77 | BACE1 (0.32) | BACE1 | |
| SCHEMBL1017026 | 0.77 | — | — | |
| SCHEMBL1017023 | 0.77 | — | — | |
| SCHEMBL8407699 | 0.77 | BACE1 (0.32) | BACE1 | |
| SCHEMBL8053017 | 0.75 | — | — | |
| SCHEMBL12446899 | 0.75 | GABRR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076496-A1 | PREPARATION OF OXINDOLE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2022-04-14 | — | — | WO | disclosed |
| EP-1043341-B1 | Use of an Ethylene/alpha-olefin Copolymer as a Base Oil in a Lubricant Composition | MITSUI CHEMICALS INC (JP) | 2008-10-01 | — | — | EP | disclosed |