Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 13/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242770 | 0.74 | SCD (1.00) | SCD | |
| SCHEMBL243920 | 0.74 | SCD (0.76) | SCDSMN1; SMN2 | |
| SCHEMBL13393741 | 0.73 | SCD (0.49) | SCDALDH1A1 | |
| SCHEMBL12717697 | 0.73 | SCD (0.62) | SCDSMN1; SMN2MAPK1FSCN1 | |
| SCHEMBL14047402 | 0.72 | SCD (0.62) | SCDGAA | |
| SCHEMBL348976 | 0.66 | SCD (0.83) | SCD | |
| SCHEMBL1911730 | 0.66 | SCD (0.84) | SCD | |
| SCHEMBL14047641 | 0.65 | SCD (0.46) | SCDSMN1; SMN2 | |
| SCHEMBL14047587 | 0.64 | TSHR (0.59) | SCDALDH1A1GAA | |
| SCHEMBL1911705 | 0.63 | SCD (0.83) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |