Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 13/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047402 | 0.91 | SCD (0.62) | SCD | |
| SCHEMBL13393740 | 0.86 | CACNA1G (0.43) | SCDALDH1A1 | |
| SCHEMBL14047625 | 0.79 | SCD (0.57) | SCDALDH1A1TSHR | |
| SCHEMBL14047400 | 0.79 | SCD (0.57) | SCDALDH1A1TSHR | |
| SCHEMBL14047406 | 0.78 | SCD (0.44) | SCDALDH1A1TSHR | |
| SCHEMBL12464377 | 0.74 | SCD (0.82) | SCD | |
| SCHEMBL14047544 | 0.73 | SCD (0.59) | SCDALDH1A1 | |
| SCHEMBL14047539 | 0.72 | SCD (0.53) | SCDALDH1A1 | |
| SCHEMBL14272811 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL14480138 | 0.70 | SCD (0.49) | SCDPTGER4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035052-A1 | TISSUE SELECTIVE STEAROYL-COA DESATURASE 1 INHIBITORS AND CELL BASED SCREENING ASSAY FOR THEIR IDENTIFICATION | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-04-01 | — | — | WO | disclosed |