Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404597 | 0.89 | BRAF (0.35) | BRAFGPR142 | |
| SCHEMBL1404662 | 0.88 | MAPK14 (0.38) | BRAF | |
| SCHEMBL1404560 | 0.86 | BRAF (0.37) | BRAFGPR142 | |
| SCHEMBL1404647 | 0.85 | BRAF (0.36) | BRAF | |
| SCHEMBL4466858 | 0.83 | BRAF (0.36) | BRAFGPR142 | |
| SCHEMBL1404811 | 0.82 | BRAF (0.38) | BRAFGPR142 | |
| SCHEMBL1404734 | 0.81 | BRAF (0.38) | BRAFGPR142 | |
| SCHEMBL1404899 | 0.81 | BRAF (0.40) | BRAFGPR142 | |
| SCHEMBL1404833 | 0.81 | BRAF (0.37) | BRAFGPR142 | |
| SCHEMBL1404576 | 0.80 | BRAF (0.39) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692116-B1 | 1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMA (US) | 2011-03-09 | — | — | EP | claimed |