Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 16/20 | 0.36 |
| ▸ | STK25 | O00506 | 1/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384089 | 0.87 | KIT (0.42) | KITSRCFLT3ITKBRAF | |
| SCHEMBL1404721 | 0.87 | BTK (0.41) | BRAFGPR142 | |
| SCHEMBL1404734 | 0.86 | BRAF (0.38) | BRAFGPR142 | |
| SCHEMBL1404899 | 0.86 | BRAF (0.40) | BRAFGPR142 | |
| SCHEMBL1404811 | 0.86 | BRAF (0.38) | BRAFGPR142 | |
| SCHEMBL1404753 | 0.85 | BRAF (0.37) | BRAFSTK25 | |
| SCHEMBL1404562 | 0.84 | BRAF (0.38) | BRAFGPR142 | |
| SCHEMBL1404560 | 0.84 | BRAF (0.37) | BRAFGPR142 | |
| SCHEMBL1404683 | 0.84 | BRAF (0.39) | BRAFGPR142 | |
| SCHEMBL1404576 | 0.84 | BRAF (0.39) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692116-B1 | 1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMA (US) | 2011-03-09 | — | — | EP | claimed |