Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.83 |
| ▸ | LYN | P07948 | 19/20 | 0.83 |
| ▸ | SRC | P12931 | 19/20 | 0.83 |
| ▸ | KDR | P35968 | 19/20 | 0.83 |
| ▸ | INSR | P06213 | 17/20 | 0.83 |
| ▸ | HCK | P08631 | 14/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467197 | 0.92 | LCK (0.84) | LCKLYNSRCKDRINSR | |
| SCHEMBL2466522 | 0.88 | LCK (0.84) | LCKLYNSRCKDRINSR | |
| SCHEMBL14029730 | 0.83 | LCK (1.00) | LCKLYNSRCKDRINSR | |
| SCHEMBL14047842 | 0.80 | LCK (0.83) | LCKLYNSRCKDRINSR | |
| SCHEMBL2465879 | 0.79 | LCK (1.00) | LCKLYNSRCKDRINSR | |
| SCHEMBL2465683 | 0.76 | LCK (0.76) | LCKLYNSRCKDRINSR | |
| SCHEMBL2466114 | 0.74 | LCK (0.74) | LCKLYNSRCKDRINSR | |
| SCHEMBL4965530 | 0.74 | LCK (1.00) | LCKLYNSRCKDRINSR | |
| SCHEMBL2469764 | 0.74 | LCK (1.00) | LCKLYNSRCKDRINSR | |
| SCHEMBL2463709 | 0.73 | LCK (0.81) | LCKLYNSRCKDRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255112-A1 | Pyrimidine-Substituted Benzimidazole Derivatives as Protein Kinase Inhibitors | IRM LLC (BM) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255112-A1 | Pyrimidine-Substituted Benzimidazole Derivatives as Protein Kinase Inhibitors | BMX, FYN, BRSK2 | LCK 14/4885LYN 36/4885SRC 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.