Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.43 |
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | BCR | P11274 | 5/20 | 0.42 |
| ▸ | STK25 | O00506 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404819 | 0.94 | BRAF (0.42) | BRAFABL1BCRSTK25 | |
| SCHEMBL1404761 | 0.93 | ABL1 (0.43) | BRAFABL1BCR | |
| SCHEMBL1381107 | 0.90 | BRAF (0.44) | BRAFABL1BCRSTK25CNR2 | |
| SCHEMBL1404811 | 0.87 | BRAF (0.38) | BRAF | |
| SCHEMBL1414023 | 0.87 | ABL1 (0.46) | BRAFABL1BCR | |
| SCHEMBL1404758 | 0.86 | BRAF (0.37) | BRAF | |
| SCHEMBL4471194 | 0.86 | BRAF (0.46) | BRAFABL1BCRSTK25 | |
| SCHEMBL1404576 | 0.85 | BRAF (0.39) | BRAF | |
| SCHEMBL1404608 | 0.85 | BRAF (0.35) | BRAF | |
| SCHEMBL5779078 | 0.85 | BRAF (0.37) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692116-B1 | 1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMA (US) | 2011-03-09 | — | — | EP | claimed |