Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14030153 | 0.88 | HPGD (0.54) | HPGDLMNAPOLBTAAR1TOP1 | |
| SCHEMBL3812477 | 0.88 | HPGD (0.56) | HPGDLMNAPOLBTAAR1TOP1 | |
| SCHEMBL3814971 | 0.86 | TOP1 (0.43) | HPGDLMNAPOLBTAAR1TOP1 | |
| SCHEMBL4388689 | 0.84 | KDM4E (0.50) | HPGDLMNATOP1KDM4EALDH1A1 | |
| SCHEMBL28334702 | 0.82 | HPGD (0.62) | HPGDLMNAPOLBTAAR1TOP1 | |
| 7-Desethyl-Norfloxacin SCHEMBL30610053 | 0.81 | TOP1 (0.70) | HPGDLMNAPOLBTAAR1TOP1 | |
| 7-Desethyl-Norfloxacin SCHEMBL5551203 | 0.81 | TOP1 (0.70) | HPGDLMNAPOLBTAAR1TOP1 | |
| 7-Desethyl-Norfloxacin SCHEMBL29548802 | 0.80 | TOP1 (0.68) | HPGDLMNAPOLBTAAR1TOP1 | |
| SCHEMBL22698659 | 0.80 | HPGD (0.65) | HPGDLMNAPOLBTAAR1TOP1 | |
| SCHEMBL6690458 | 0.78 | TOP1 (0.61) | HPGDLMNAPOLBTAAR1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255060-A1 | Ester Linked Macrolides Useful For The Treatment of Microbial Infections | GLAXOSMITHKLINE ISTRAZIVACKI CENTER ZAGREB (HR) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255060-A1 | Ester Linked Macrolides Useful For The Treatment of Microbial Infections | CYP51A1, TLR5, MALT1 | HPGD 1842/4885LMNA 2596/4885POLB 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.