Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24684871 | 0.89 | KMT2A (0.36) | HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL669086 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL10481443 | 0.87 | — | — | |
| SCHEMBL28245004 | 0.80 | EPHX2 (0.36) | HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL668274 | 0.79 | — | — | |
| SCHEMBL668240 | 0.79 | — | — | |
| SCHEMBL363035 | 0.78 | TP53 (0.47) | SMN1; SMN2 | |
| SCHEMBL473626 | 0.78 | TP53 (0.47) | SMN1; SMN2 | |
| SCHEMBL24683904 | 0.78 | TP53 (0.47) | SMN1; SMN2 | |
| SCHEMBL15760044 | 0.78 | EPHX1 (0.33) | HTTKMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385982-B1 | METHODS AND MEANS FOR DETECTING ENZYMATIC CLEAVAGE AND LINKAGE REACTIONS | EVOTEC AG (DE) | 2008-10-22 | — | — | EP | disclosed |