Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293759 | 0.91 | P2RY6 (0.64) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL17702684 | 0.90 | P2RY6 (0.64) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL15493524 | 0.90 | P2RY6 (0.71) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL12716296 | 0.90 | P2RY6 (0.62) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL31756958 | 0.89 | P2RY6 (0.69) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL22204520 | 0.89 | P2RY6 (0.69) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL18716036 | 0.88 | P2RY6 (0.68) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL16377535 | 0.88 | P2RY6 (0.68) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL18089786 | 0.87 | P2RY6 (0.61) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL14013426 | 0.87 | P2RY6 (0.67) | P2RY6MEN1THRBRECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385982-B1 | METHODS AND MEANS FOR DETECTING ENZYMATIC CLEAVAGE AND LINKAGE REACTIONS | EVOTEC AG (DE) | 2008-10-22 | — | — | EP | disclosed |
| US-7425425-B2 | Method for the detection of enzyme-catalyzed cleavage reactions by fluorescence spectroscopy | EVOTEC OAI AG (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20070122863-A1 | Methods and means for the detection of enzyme-catalyzed cleavage and linking reactions | EVOTEC OAI AG. | 2007-05-31 | — | — | US | disclosed |