Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049043 | 0.87 | P2RY6 (0.67) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL14013426 | 0.85 | P2RY6 (0.67) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL15493524 | 0.85 | P2RY6 (0.71) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL17702684 | 0.85 | P2RY6 (0.64) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL10293759 | 0.85 | P2RY6 (0.64) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL18716036 | 0.85 | P2RY6 (0.68) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL16377535 | 0.83 | P2RY6 (0.68) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL12716296 | 0.83 | P2RY6 (0.62) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL13024610 | 0.82 | P2RY6 (0.67) | P2RY6CA12CA1CA2CA9 | |
| SCHEMBL22204520 | 0.82 | P2RY6 (0.69) | P2RY6CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160271261-A1 | TRIORTHOGONAL REAGENTS FOR DUAL PROTEIN CONJUGATION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271261-A1 | TRIORTHOGONAL REAGENTS FOR DUAL PROTEIN CONJUGATION | FNTA, FNTB, GNPAT | P2RY6 4102/4885CA12 4579/4885CA1 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.