SCHEMBL14049571

SCHEMBL14049571

CC(C)CC1(Cc2ccc(N)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.41
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
GFER P55789 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.35
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
PPID Q08752 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30279705 0.79 CYP3A4 (0.41) CYP19A1TDP1ALDH1A1GFERCYP3A4
SCHEMBL24434485 0.78 ALDH1A1 (0.39) CYP19A1ALDH1A1CYP3A4TSHRLOXL2
SCHEMBL28409253 0.72 ALDH1A1 (0.48) TDP1ALDH1A1GFERCYP3A4TSHR
SCHEMBL23719251 0.68 IDO1 (0.41) TDP1ALDH1A1L3MBTL1MEN1GAA
SCHEMBL1823450 0.67 MAOB (0.64) CYP19A1TDP1ALDH1A1GFERCYP3A4
SCHEMBL2406779 0.66 TSHR (0.50) TDP1ALDH1A1GFERCYP3A4TSHR
SCHEMBL3790148 0.66 ALDH1A1 (0.33) CYP19A1TDP1ALDH1A1GFERCYP3A4
SCHEMBL4341772 0.64 ALDH1A1 (0.48) TDP1ALDH1A1GFERCYP3A4TSHR
SCHEMBL1820867 0.64 MAOB (0.54) TDP1ALDH1A1GFERCYP3A4TSHR
SCHEMBL23123018 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7438833-B2 Organic species that facilitate charge transfer to or from nanostructures NANOSYS, INC. (US) 2008-10-21 US disclosed