Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12828973 | 1.00 | HSD17B10 (0.49) | HSD17B10TDP1ACHENR1H4POLB | |
| SCHEMBL14083503 | 0.93 | ACHE (0.49) | HSD17B10TDP1ACHENR1H4HSD11B1 | |
| SCHEMBL22360569 | 0.90 | ACHE (0.44) | HSD17B10TDP1ACHEPOLBRECQL | |
| SCHEMBL10459116 | 0.85 | NR1H4 (0.43) | HSD17B10TDP1NR1H4PTPN1GPBAR1 | |
| SCHEMBL22360570 | 0.84 | ACHE (0.49) | ACHEHSD11B1PTPN1GPBAR1 | |
| SCHEMBL19092745 | 0.83 | SLC10A1 (0.51) | HSD17B10TDP1ACHEHSD11B1PTPN1 | |
| SCHEMBL13781789 | 0.83 | SLC10A1 (0.51) | HSD17B10TDP1ACHEHSD11B1PTPN1 | |
| SCHEMBL14628350 | 0.83 | NR1H4 (0.66) | HSD17B10TDP1NR1H4POLBRECQL | |
| SCHEMBL14049825 | 0.83 | NR1H4 (0.66) | HSD17B10TDP1NR1H4POLBRECQL | |
| SCHEMBL22360709 | 0.83 | PTPN2 (0.42) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924361-B1 | NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LTD (IN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2021161206-A1 | NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2021-08-19 | — | — | WO | disclosed |
| WO-2020165741-A1 | NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2020-08-20 | — | — | WO | disclosed |
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |