Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064823 | 0.64 | CYP1A2 (0.36) | — | |
| SCHEMBL19052298 | 0.61 | — | — | |
| SCHEMBL10099731 | 0.60 | — | — | |
| SCHEMBL2050563 | 0.60 | — | — | |
| SCHEMBL18901321 | 0.59 | ALDH1A1 (0.32) | ALDH1A1ALOX15 | |
| SCHEMBL14034584 | 0.58 | DRD3 (0.30) | — | |
| SCHEMBL11233670 | 0.58 | — | — | |
| SCHEMBL17016462 | 0.57 | HDAC1 (0.30) | — | |
| SCHEMBL1053003 | 0.57 | — | — | |
| SCHEMBL1145933 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129080-A1 | 4, 6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |