Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12439804 | 0.79 | IGF1R (0.59) | IGF1R | |
| SCHEMBL14311371 | 0.78 | IGF1R (0.40) | IGF1R | |
| SCHEMBL12438239 | 0.74 | IGF1R (0.68) | IGF1R | |
| SCHEMBL14050388 | 0.65 | IGF1R (0.38) | IGF1R | |
| SCHEMBL12438270 | 0.59 | IGF1R (0.61) | IGF1R | |
| SCHEMBL12439395 | 0.58 | IGF1R (0.60) | IGF1R | |
| SCHEMBL14161978 | 0.58 | IGF1R (0.61) | IGF1R | |
| SCHEMBL12439792 | 0.58 | IGF1R (0.60) | IGF1R | |
| SCHEMBL14320002 | 0.57 | IGF1R (0.49) | IGF1R | |
| SCHEMBL12438231 | 0.53 | IGF1R (0.42) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127594-A2 | COMBINATION THERAPIES COMPRISING QUINOXALINE INHIBITORS OF PI3K-ALPHA FOR USE IN THE TREATMENT OF CANCER | EXELIXIS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |