Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | CKS1B | P61024 | 2/20 | 0.33 |
| ▸ | SKP1 | P63208 | 2/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.33 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413687 | 0.86 | BTK (0.48) | JAK3BTKRETCKS1BSKP1 | |
| SCHEMBL14050997 | 0.85 | JAK3 (0.37) | JAK3BTKBCL6CSNK2A1RET | |
| SCHEMBL14050908 | 0.82 | TYK2 (0.39) | JAK3BTKBCL6TYK2GSK3B | |
| SCHEMBL17690946 | 0.76 | CKS1B (0.49) | GPR119CKS1BSKP1SKP2GALR2 | |
| SCHEMBL14413677 | 0.75 | CKS1B (0.48) | RETGPR119CKS1BSKP1SKP2 | |
| SCHEMBL14413691 | 0.75 | BTK (0.45) | JAK3BTKCKS1BSKP1SKP2 | |
| SCHEMBL14051087 | 0.74 | BCL6 (0.38) | JAK3BTKBCL6EGLN2CSNK2A1 | |
| SCHEMBL14413660 | 0.74 | CKS1B (0.45) | RETGPR119CKS1BSKP1SKP2 | |
| SCHEMBL14051076 | 0.73 | USP2 (0.41) | BCL6TYK2EGLN2CSNK2A1 | |
| SCHEMBL14413674 | 0.72 | CKS1B (0.51) | JAK3BTKRETCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130569-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |