SCHEMBL1405136

SCHEMBL1405136

COc1ccc(N=Nc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.59
ALDH1A1 P00352 3/20 0.57
LTA4H P09960 2/20 0.56
MAPT P10636 8/20 0.56
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
TDP1 Q9NUW8 5/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
LMNA P02545 3/20 0.56
MAPK1 P28482 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
POLB P06746 1/20 0.56
PTGS2 P35354 1/20 0.55
HTT P42858 2/20 0.54
GSK3B P49841 1/20 0.54
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405134 1.00 CA4 (0.59) CA4ALDH1A1LTA4HMAPTMEN1
SCHEMBL28006858 0.94 CA4 (0.52) CA4ALDH1A1LTA4HMAPTMEN1
SCHEMBL5426092 0.94 L3MBTL1 (0.64) CA4ALDH1A1LTA4HMAPTMEN1
SCHEMBL1405602 0.90 CA1 (0.65) MAPTMEN1KMT2ATDP1L3MBTL1
SCHEMBL1405603 0.90 CA1 (0.65) MAPTMEN1KMT2ATDP1L3MBTL1
Phenol SCHEMBL28327458 0.90 KMT2A (0.63) CA4LTA4HMAPTMEN1KMT2A
SCHEMBL28233592 0.88 MAPT (0.63) CA4ALDH1A1MAPTMEN1KMT2A
SCHEMBL28233594 0.88 MAPT (0.63) CA4ALDH1A1MAPTMEN1KMT2A
SCHEMBL4392260 0.86 CA4 (0.59) CA4ALDH1A1LTA4HMAPTTDP1
Anisole SCHEMBL10608079 0.86 MAPT (0.69) CA4ALDH1A1LTA4HMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719270-A2 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL RxSight, Inc. (US) 2026-04-08 EP claimed
EP-4719269-A2 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL RxSight, Inc. (US) 2026-04-08 EP claimed
EP-4719268-A2 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL RxSight, Inc. (US) 2026-04-08 EP claimed
EP-4044967-B1 LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER RXSIGHT INC (US) 2025-09-24 EP claimed
US-20250230056-A1 MEDICAL TUBING HAVING DIFFERING COLOR STATES CAREFUSION 303, INC. 2025-07-17 US claimed
CN-114514003-B Adjustable intraocular lens with a modulatable pre-absorption protective layer RX视觉股份有限公司 2025-05-27 CN claimed
CN-119955369-A Micro-LED laser massive transfer release material and preparation method and application thereof 深圳市化讯半导体材料有限公司 2025-05-09 CN claimed
EP-4547311-A1 MEDICAL TUBING HAVING DIFFERING COLOR STATES CareFusion 303, Inc. (US) 2025-05-07 EP claimed
US-12291462-B2 Medical tubing having differing color states CAREFUSION 303, INC. (US) 2025-05-06 US claimed
US-20240407911-A1 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH ADVANCED POLYMERIZATION CONTROL RXSIGHT, INC. (US) 2024-12-12 US claimed
CN-116373056-A Flexible intelligent wood with responsiveness function, actuator and preparation method 南京林业大学 2023-07-04 CN claimed
CN-114230759-B Synthesis method of hydrolysis-resistant high-color-fastness aqueous polyurethane emulsion 江苏华缘高科股份有限公司 2023-05-19 CN claimed
EP-4044967-A1 LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER RxSight, Inc. (US) 2022-08-24 EP claimed
CN-114514003-A Accommodating intraocular lens with accommodating anterior protective layer RX视觉股份有限公司 2022-05-17 CN claimed
US-20220142770-A1 LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER RXSIGHT, INC. 2022-05-12 US claimed
CN-114230759-A Synthesis method of hydrolysis-resistant high-color-fastness aqueous polyurethane emulsion 江苏华缘高科股份有限公司 2022-03-25 CN claimed
US-11266495-B2 Light adjustable intraocular lens with a modulable absorption front protection layer RXSIGHT, INC. (US) 2022-03-08 US claimed
WO-2021081013-A1 LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER RXSIGHT, INC. (US) 2021-04-29 WO claimed
US-20210113328-A1 LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER RXSIGHT, INC. (US) 2021-04-22 US claimed
CN-106928406-A A kind of adhesive polyester of adjustable viscosity and preparation method thereof 苏州瀚海新材料有限公司 2017-07-07 CN claimed