SCHEMBL1405684

SCHEMBL1405684

CCCCC[CH]N(CCCC)CCCC

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
DNM1 Q05193 6/20 0.36
FAAH O00519 2/20 0.36
TRPV1 Q8NER1 2/20 0.36
THRB P10828 1/20 0.35
ALDH1A1 P00352 1/20 0.33
EP300 Q09472 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5958083 0.97 TSHR (0.44) TSHRDNM1FAAHTRPV1THRB
SCHEMBL317337 0.97 TSHR (0.44) TSHRDNM1FAAHTRPV1THRB
SCHEMBL8318187 0.92 DNM1 (0.46) TSHRDNM1FAAHTRPV1THRB
SCHEMBL1405657 0.92 DNM1 (0.46) TSHRDNM1FAAHTRPV1THRB
SCHEMBL8321451 0.92 DNM1 (0.46) TSHRDNM1FAAHTRPV1THRB
SCHEMBL10887715 0.92 DNM1 (0.46) TSHRDNM1FAAHTRPV1THRB
SCHEMBL3027388 0.92 TSHR (0.39) TSHRDNM1THRBALDH1A1
SCHEMBL15900023 0.90 DNM1 (0.42) TSHRDNM1FAAHTRPV1THRB
SCHEMBL4537881 0.90 TSHR (0.40) TSHRDNM1FAAHTRPV1THRB
SCHEMBL8746000 0.87 TSHR (0.44) TSHRDNM1FAAHTRPV1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623579-B2 Easily dispersible pigment preparation based on C.I. pigment yellow 155 CLARIANT FINANCE (BVI) LIMITED (VG) 2014-01-07 US disclosed
EP-2319882-B1 POLYOLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2013-10-09 EP disclosed
US-20120282543-A1 Easily Dispersible Pigment Preparation Based on C.I. Pigment Yellow 155 CLARIANT FINANCE (BVI) LIMITED (VG) 2012-11-08 US disclosed
US-8288462-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2012-10-16 US disclosed
US-20110218279-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-09-08 US disclosed
EP-2319882-A1 POLYOLEFIN RESIN COMPOSITION Adeka Corporation (JP) 2011-05-11 EP disclosed
EP-1697936-B1 NOVEL OPTICAL STORAGE MATERIALS BASED ON NARROWBAND OPTICAL PROPERTIES GEN ELECTRIC (US) 2011-03-09 EP disclosed
US-7829567-B2 Imino-indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2010-11-09 US disclosed
US-20090111987-A1 Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2009-04-30 US disclosed
EP-1697936-A1 NOVEL OPTICAL STORAGE MATERIALS BASED ON NARROWBAND OPTICAL PROPERTIES GENERAL ELECTRIC COMPANY (US) 2006-09-06 EP disclosed
EP-0149093-B1 N-GLYCOSYLATED UREAS, CARBAMATES AND THIOCARBAMATES, THEIR PREPARATION METHOD AND THEIR USE BAYER AG (DE) 1989-05-31 EP disclosed
EP-0143385-B1 PHOSPHORYLISED GLYCOSIL AMIDES, UREAS, CARBAMATES AND THIOCARBAMATES, METHOD FOR THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1989-03-15 EP disclosed
US-4737488-A Immune system-stimulating N-glycosylated ureas and carbamates BAYER AKTIENGESELLSCHAFT (DE) 1988-04-12 US disclosed
US-4686208-A Phosphorylated glycosyl-amides, -ureas, -carbamates and -thiocarbamates and method of use BAYER AKTIENGESELLSCHAFT (DE) 1987-08-11 US disclosed
EP-0155625-A2 Glycolipid-like substances in liposome form BAYER AG (DE) 1985-09-25 EP disclosed
EP-0149093-A2 N-glycosylated ureas, carbamates and thiocarbamates, their preparation method and their use BAYER AG (DE) 1985-07-24 EP disclosed
EP-0143385-A2 Phosphorylised glycosil amides, ureas, carbamates and thiocarbamates, method for their preparation and their use BAYER AG (DE) 1985-06-05 EP disclosed
EP-0055728-A4 HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE. GOODRICH CO B F (US) 1982-08-11 EP disclosed
EP-0055728-A1 HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE The B.F. GOODRICH Company (US) 1982-07-14 EP disclosed
WO-1982000147-A1 HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE GOODRICH CO B F (US) 1982-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111987-A1 Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same IMPA1, IMPDH1, IPO5 TSHR 4307/4885DNM1 1313/4885FAAH 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.