Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853442 | 1.00 | LTA4H (0.48) | LTA4HSMYD3F2ST14PRSS1 | |
| SCHEMBL13743 | 0.91 | BCHE (0.43) | LTA4HSMYD3F2ST14PRSS1 | |
| SCHEMBL19719305 | 0.83 | SMYD3 (0.42) | LTA4HSMYD3F2ST14PRSS1 | |
| SCHEMBL14853439 | 0.83 | SMYD3 (0.42) | LTA4HSMYD3F2ST14PRSS1 | |
| SCHEMBL17354490 | 0.83 | SMYD3 (0.42) | LTA4HSMYD3F2ST14PRSS1 | |
| SCHEMBL13781 | 0.81 | LTA4H (0.43) | LTA4HBCHECHRM3SIGMAR1CACNA1H | |
| SCHEMBL14250 | 0.81 | LTA4H (0.43) | LTA4HBCHECHRM3SIGMAR1CACNA1H | |
| SCHEMBL14394 | 0.81 | LTA4H (0.43) | LTA4HBCHECHRM3SIGMAR1CACNA1H | |
| SCHEMBL14850302 | 0.80 | CACNA1H (0.50) | SMYD3F2ST14PRSS1PRSS2 | |
| SCHEMBL17485873 | 0.80 | KDM5A (0.41) | SMYD3F2ST14PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |