Propene

Propene

SCHEMBL14059331

C=CC.C=CC.COCCOC(=O)c1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
LMNA P02545 2/20 0.59
TDP1 Q9NUW8 2/20 0.58
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HSP90AA1 P07900 1/20 0.49
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
MAPK1 P28482 1/20 0.47
HIF1A Q16665 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ABCB11 O95342 1/20 0.45
CYP3A4 P08684 1/20 0.45
ADRA2B P18089 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL2507960 1.00 TSHR (0.59) TSHRLMNATDP1KMT2AKDM4E
Propene SCHEMBL4455281 0.93 LMNA (0.67) TSHRLMNATDP1KMT2ASMN1; SMN2
Propene SCHEMBL6431713 0.93 LMNA (0.67) TSHRLMNATDP1KMT2ASMN1; SMN2
Propene SCHEMBL4012587 0.93 LMNA (0.67) TSHRLMNATDP1KMT2ASMN1; SMN2
Propene SCHEMBL6062789 0.93 LMNA (0.67) TSHRLMNATDP1KMT2ASMN1; SMN2
SCHEMBL514995 0.91 TSHR (0.69) TSHRLMNATDP1KMT2AKDM4E
Hydrochloric Acid SCHEMBL28478926 0.90 TSHR (0.67) TSHRLMNATDP1KMT2AKDM4E
Ammonia Solution, Strong SCHEMBL27732716 0.90 TSHR (0.67) TSHRLMNATDP1KMT2AKDM4E
Propene SCHEMBL16044977 0.88 LMNA (0.61) TSHRLMNATDP1KMT2ASMN1; SMN2
Propene SCHEMBL3957158 0.87 LMNA (0.59) TSHRLMNATDP1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110354834-B Preparation method and application of magnesium-aluminum-zirconium composite oxide catalyst 常州大学 2022-06-28 CN disclosed
US-10633545-B2 Alcohol-resistant, chemically-strippable floor coating and composition for making same DIVERSEY, INC. (US) 2020-04-28 US disclosed
US-20190023907-A1 ALCOHOL-RESISTANT, CHEMICALLY-STRIPPABLE FLOOR COATING AND COMPOSITION FOR MAKING SAME THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2019-01-24 US disclosed
EP-3344675-A1 ALCOHOL-RESISTANT, CHEMICALLY-STRIPPABLE FLOOR COATING AND COMPOSITION FOR MAKING SAME Diversey, Inc. (US) 2018-07-11 EP disclosed
WO-2017040662-A1 ALCOHOL-RESISTANT, CHEMICALLY-STRIPPABLE FLOOR COATING AND COMPOSITION FOR MAKING SAME DIVERSEY, INC. (US) 2017-03-09 WO disclosed
US-20140087156-A1 SURFACE COATING SYSTEM AND METHOD OF MAKING AND USING SAME DIVERSEY, INC. (US) 2014-03-27 US disclosed
WO-2012162641-A2 SURFACE COATING SYSTEM AND METHOD OF MAKING AND USING SAME DIVERSEY, INC. (US) 2012-11-29 WO disclosed