Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 13/20 | 0.74 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.74 |
| ▸ | AVPR1B | P47901 | 8/20 | 0.74 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497344 | 0.98 | OXTR (0.75) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| SCHEMBL15511428 | 0.92 | OXTR (0.82) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| Argiprestocin SCHEMBL30424966 | 0.92 | OXTR (0.86) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| Vasotocin SCHEMBL13331 | 0.92 | OXTR (0.86) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| Vasotocin SCHEMBL15511393 | 0.92 | OXTR (0.86) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| Vasotocin SCHEMBL15511347 | 0.92 | OXTR (0.86) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| SCHEMBL15511015 | 0.90 | OXTR (0.86) | OXTRAVPR1AAVPR1BAVPR2 | |
| Vasopressin SCHEMBL1172390 | 0.88 | AVPR1A (0.95) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| SCHEMBL15511399 | 0.87 | AVPR1A (0.78) | OXTRAVPR1AAVPR1BAVPR2PTGS1 | |
| SCHEMBL29618038 | 0.86 | OXTR (0.86) | OXTRAVPR1AAVPR1BAVPR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140066373-A1 | TREATING DIABETES WITH OXYTOCIN OR OXYTOCIN ANALOGS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2014-03-06 | — | — | US | disclosed |
| WO-2012161746-A1 | USE OF OXYTOCIN OR OXYTOCIN ANALOGUES TO TREAT OBESITY AND DIABETES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-11-29 | — | — | WO | disclosed |