Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15762708 | 1.00 | PTPN1 (0.43) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL29400507 | 0.88 | ALB (0.48) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL5062433 | 0.88 | ALB (0.48) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL9359175 | 0.88 | ALB (0.48) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL14060845 | 0.86 | PTPN1 (0.46) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL13021161 | 0.85 | PTPN1 (0.46) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL15754928 | 0.85 | PTPN1 (0.39) | PTPN1MDM4TP53CASP3ALDH1A1 | |
| SCHEMBL3868341 | 0.84 | PTPN1 (0.46) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL18362192 | 0.84 | EPHX2 (0.47) | PTPN1EPHX2MDM4TP53CASP3 | |
| SCHEMBL14582839 | 0.84 | EPHX2 (0.47) | PTPN1EPHX2MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2712357-B1 | MODIFIED TYROSINE AMINO ACIDS, PEPTIDES CONTAINING THEM, AND THEIR USE FOR DETECTING HYDROLASE ENZYME ACTIVITY | PAMGENE BV (NL) | 2018-04-04 | — | — | EP | disclosed |
| US-9448237-B2 | Modified tyrosine amino acids, peptides containing them, and their use for detecting hydrolase enzyme activity | PAMGENE B.V. (NL) | 2016-09-20 | — | — | US | disclosed |
| US-20140231783-A1 | MATERIAL FOR ORGANIC ELECTRONIC DEVICE, AND ORGANIC ELECTRONIC DEVICE USING SAME | LG CHEM, LTD. (KR) | 2014-08-21 | — | — | US | disclosed |
| US-20140155286-A1 | MODIFIED TYROSINE AMINO ACIDS, PEPTIDES CONTAINING THEM, AND THEIR USE FOR DETECTING HYDROLASE ENZYME ACTIVITY | PAMGENE B.V. (NL) | 2014-06-05 | — | — | US | disclosed |
| WO-2012159997-A1 | MODIFIED TYROSINE AMINO ACIDS, PEPTIDES CONTAINING THEM, AND THEIR USE FOR DETECTING HYDROLASE ENZYME ACTIVITY | PAMGENE B.V. (NL) | 2012-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155286-A1 | MODIFIED TYROSINE AMINO ACIDS, PEPTIDES CONTAINING THEM, AND THEIR USE FOR DETECTING HYDROLASE ENZYME ACTIVITY | PTMS, TH, TYR | PTPN1 74/4885EPHX2 201/4885MDM4 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.