Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732777 | 0.89 | PTPN1 (0.51) | PTPN1GRB2MDM4TP53MDM2 | |
| SCHEMBL5062433 | 0.87 | ALB (0.48) | PTPN1ALBIL2GRB2MDM4 | |
| SCHEMBL29400507 | 0.87 | ALB (0.48) | PTPN1ALBIL2GRB2MDM4 | |
| SCHEMBL9359175 | 0.87 | ALB (0.48) | PTPN1ALBIL2GRB2MDM4 | |
| SCHEMBL14060727 | 0.84 | PTPN1 (0.43) | PTPN1ALBIL2GRB2MDM4 | |
| SCHEMBL15762708 | 0.84 | PTPN1 (0.43) | PTPN1ALBIL2GRB2MDM4 | |
| SCHEMBL1738291 | 0.83 | MDM4 (0.47) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL5494326 | 0.83 | MDM4 (0.47) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL9735223 | 0.80 | PTPN1 (0.45) | PTPN1GRB2MDM4TP53EPHX2 | |
| SCHEMBL30861897 | 0.79 | PTPN1 (0.51) | PTPN1MDM4TP53MDM2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527934-B2 | Labeled substrate conjugates for identifying enzyme inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-05 | — | — | US | disclosed |
| US-20060057658-A1 | Labeled substrate conjugates for identifying enzyme inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-03-16 | — | — | US | disclosed |