Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.45 |
| ▸ | USP5 | P45974 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14062780 | 0.96 | HCRTR2 (0.43) | HCRTR2USP5HDAC6CCR2ALDH1A1 | |
| SCHEMBL14062787 | 0.89 | HCRTR2 (0.38) | HCRTR2USP5ALDH1A1TP53CYP3A4 | |
| SCHEMBL14062604 | 0.89 | HCRTR2 (0.40) | HCRTR2USP5HDAC6ALDH1A1TP53 | |
| SCHEMBL14062801 | 0.87 | HCRTR2 (0.37) | HCRTR2USP5HDAC6CCR2ALDH1A1 | |
| SCHEMBL14062887 | 0.86 | HCRTR2 (0.37) | HCRTR2USP5HDAC6 | |
| SCHEMBL14062779 | 0.86 | HCRTR2 (0.39) | HCRTR2USP5HDAC6TSHR | |
| SCHEMBL14063160 | 0.85 | CYP3A4 (0.37) | HCRTR2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL14062593 | 0.85 | HCRTR2 (0.38) | HCRTR2 | |
| SCHEMBL14062574 | 0.84 | HCRTR2 (0.42) | HCRTR2USP5ALDH1A1HTR2ATDP1 | |
| SCHEMBL14062804 | 0.83 | HCRTR2 (0.34) | HCRTR2USP5ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |