Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 4/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14062735 | 0.96 | HCRTR2 (0.40) | HCRTR2SLC18A3HTR1ADRD2HTR2A | |
| SCHEMBL14062803 | 0.96 | HCRTR2 (0.40) | HCRTR2SLC18A3HTR1ADRD2HTR2A | |
| SCHEMBL14062893 | 0.92 | HCRTR2 (0.39) | HCRTR2SLC18A3HTR1ADRD2HTR2A | |
| SCHEMBL14062674 | 0.88 | HCRTR2 (0.38) | HCRTR2SLC18A3HTR1ADRD2HTR2A | |
| SCHEMBL14062732 | 0.85 | HCRTR2 (0.36) | HCRTR2SLC18A3HTR1ADRD2HTR2A | |
| SCHEMBL14062793 | 0.85 | HCRTR2 (0.36) | HCRTR2SLC18A3HTR1ADRD2HTR2A | |
| SCHEMBL14062585 | 0.84 | DRD2 (0.43) | HCRTR2SLC18A3HTR1ADRD2HTR2A | |
| SCHEMBL14062639 | 0.84 | ALDH1A1 (0.38) | HCRTR2SLC18A3ALDH1A1GLAUSP5 | |
| SCHEMBL14062805 | 0.84 | KMT2A (0.41) | HCRTR2DRD2ALDH1A1USP5 | |
| SCHEMBL14062607 | 0.84 | HCRTR2 (0.45) | HCRTR2HTR2AALDH1A1USP5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |