SCHEMBL1406280

SCHEMBL1406280

SN(c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
INSR P06213 1/20 0.39
IGF1R P08069 1/20 0.39
CYP2A6 P11509 5/20 0.38
CYP1A2 P05177 3/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
GSTP1 P09211 1/20 0.38
HPGD P15428 1/20 0.38
RELA Q04206 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27411165 0.79 CYP2A6 (0.42) ALDH1A1INSRIGF1RCYP2A6CYP1A2
SCHEMBL289249 0.78 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP3A4TDP1L3MBTL1
SCHEMBL1035098 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R
SCHEMBL15968959 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R
SCHEMBL23896 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R
SCHEMBL23264367 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R
SCHEMBL23264551 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R
SCHEMBL23264340 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R
SCHEMBL13720527 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R
SCHEMBL23264365 0.77 ALDH1A1 (0.50) ALDH1A1LMNATP53INSRIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8680030-B2 Enhanced deposit control for lubricating oils used under sustained high load conditions employing glycerine derivative with a grafted hindered phenolic and/or a hindered phenolic containing a thioether group EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-03-25 US disclosed
EP-0958338-B1 LITHIUM COMPLEX GREASE WITH EXTENDED LUBRICATION LIFE EXXONMOBIL RES & ENG CO (US) 2011-03-09 EP disclosed
EP-1987116-A2 ENHANCED DEPOSIT CONTROL FOR LUBRICATING OILS USED UNDER SUSTAINED HIGH LOAD CONDITIONS ExxonMobil Research and Engineering Company (US) 2008-11-05 EP disclosed
EP-1969103-A2 ENHANCED DEPOSIT CONTROL FOR LUBRICATING OILS USED UNDER SUSTAINED HIGH LOAD CONDITIONS EMPLOYING GLYCERINE DERIVATIVE WITH A GRAFTED HINDERED PHENOLIC AND/OR A HINDERED PHENOLIC CONTAINING A THIOETHER GROUP ExxonMobil Research and Engineering Company (US) 2008-09-17 EP disclosed
WO-2007061699-A2 ENHANCED DEPOSIT CONTROL FOR LUBRICATING OILS USED UNDER SUSTAINED HIGH LOAD CONDITIONS EMPLOYING GLYCERINE DERIVATIVE WITH A GRAFTED HINDERED PHENOLIC AND/OR A HINDERED PHENOLIC CONTAINING A THIOETHER GROUP EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-05-31 WO disclosed
WO-2007061698-A2 ENHANCED DEPOSIT CONTROL FOR LUBRICATING OILS USED UNDER SUSTAINED HIGH LOAD CONDITIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-05-31 WO disclosed
US-20070117726-A1 Enhanced deposit control for lubricating oils used under sustained high load conditions CARTWRIGHT STANLEY J 2007-05-24 US disclosed
US-20070117724-A1 Enhanced deposit control for lubricating oils used under sustained high load conditions employing glycerine derivative with a grafted hindered phenolic and/or a hindered phenolic containing a thioether group EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-05-24 US disclosed
EP-1250407-B1 LONG LIFE MEDIUM AND HIGH ASH OILS WITH ENHANCED NITRATION RESISTANCE EXXONMOBIL RES & ENG CO (US) 2006-03-15 EP disclosed
EP-1250406-B1 LONG LIFE LUBRICATING OIL COMPOSITION USING PARTICULAR DETERGENT MIXTURE EXXONMOBIL RES & ENG CO (US) 2005-11-16 EP disclosed
US-6191081-B1 OIL LUBRICANT AND METAL SALT OF SALICYLATE, METAL SULFONATE, METAL PHENATE AND MIXTURES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2001-02-20 US disclosed
US-6140282-A LUBRICATING BASE OIL AND A MINOR AMOUNT OF A MIXTURE OF HIGH TOTAL BASE NUMBER(TBN), MEDIUM TBN AND LOW/NEUTRAL TBN DETERGENTS WHEREIN METAL SALICYLATE DETERGENT IS AT LEAST ONE OF THE MEDIUM OR LOW/NEUTRAL TBN DETERGENTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2000-10-31 US disclosed
EP-1002027-A4 GREASE CONTAINING DIAMINE CORROSION INHIBITORS EXXON RESEARCH ENGINEERING CO (US) 2000-05-24 EP disclosed
EP-1002027-A1 GREASE CONTAINING DIAMINE CORROSION INHIBITORS EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-05-24 EP disclosed
EP-0903398-A2 Lubricating grease containing alkoxylated amine corrosion inhibitor EXXON RESEARCH AND ENGINEERING COMPANY (US) 1999-03-24 EP disclosed
US-5851969-A Grease containing diamine corrosion inhibitors EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-12-22 US disclosed
EP-0867500-A1 Preparation of polyalphaolefin based greases EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-09-30 EP disclosed
WO-1998041599-A1 GREASE CONTAINING DIAMINE CORROSION INHIBITORS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-09-24 WO disclosed
US-5783531-A FORMING A THICKENER BY COMBINING LITHIUM, CALCIUM, BARIUM OR ALUMINUM SOAPS OR COMPLEXES WITH FIRST POLYALPHAOLEFIN HAVING LOWER VISCOSITY THAN FINAL BASE OIL, ADDING SECOND OLEFIN POLYMER WITH HIGHER VISCOSITY THAN FINAL BASE OIL EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-07-21 US disclosed
US-5731274-A Lithium complex grease with extended lubrication life EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070117726-A1 Enhanced deposit control for lubricating oils used under sustained high load conditions TAF1, TAF5, TAF9 ALDH1A1 3722/4885LMNA 1746/4885TP53 4000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.