Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063004 | 0.92 | ALDH1A1 (0.41) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14063038 | 0.91 | ALDH1A1 (0.42) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14063012 | 0.86 | TDP1 (0.40) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14063154 | 0.85 | TSHR (0.46) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14063029 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14062855 | 0.83 | FFAR4 (0.38) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14063011 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14062986 | 0.80 | TDP1 (0.44) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14063020 | 0.78 | RARG (0.38) | MAPTFFAR1PPARDFFAR4RARG | |
| SCHEMBL14062922 | 0.78 | MAOB (0.38) | SMN1; SMN2FFAR1FFAR4GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |