Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.50 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.50 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.50 |
| ▸ | GJB2 | P29033 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 3/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.41 |
| ▸ | CDC25B | P30305 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259552 | 1.00 | SSTR1 (0.50) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL264459 | 1.00 | SSTR1 (0.50) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL260045 | 0.95 | HTR1A (0.50) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL17114325 | 0.95 | HTR1A (0.50) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL259789 | 0.95 | HTR1A (0.50) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL260046 | 0.95 | HTR1A (0.50) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL17114324 | 0.95 | HTR1A (0.50) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL9763007 | 0.86 | SSTR1 (0.51) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL27424638 | 0.85 | PDE2A (0.46) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL25353926 | 0.83 | SSTR1 (0.65) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429571-B2 | Therapeutic furopyrimidines and thienopyrimidines | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-09-30 | — | — | US | disclosed |