SCHEMBL14064241

SCHEMBL14064241

OC1CCC(CCc2ccc(-c3cc(F)c(F)c(F)c3)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.43
MAOB P27338 4/20 0.36
CTSC P53634 2/20 0.35
F10 P00742 1/20 0.35
KIF11 P52732 1/20 0.35
RARB P10826 2/20 0.33
RARA P10276 1/20 0.33
RARG P13631 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP17A1 P05093 1/20 0.32
CYP21A2 P08686 1/20 0.32
CYP11B1 P15538 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14064203 0.96 GPR84 (0.40) GPR84MAOBCTSCF10KIF11
SCHEMBL14064240 0.88 GPR84 (0.43) GPR84MAOBKIF11RARBRARA
SCHEMBL8814984 0.85 GPR84 (0.40) GPR84MAOBCTSCF10RARB
SCHEMBL9763594 0.85 HRH3 (0.45) GPR84MAOBCTSCF10RARB
SCHEMBL8027617 0.85 GPR84 (0.40) GPR84MAOBCTSCF10RARB
SCHEMBL9504614 0.85 GPR84 (0.40) GPR84MAOBCTSCF10RARB
SCHEMBL9763604 0.85 HRH3 (0.45) GPR84MAOBCTSCF10RARB
SCHEMBL13345628 0.85 GPR84 (0.40) GPR84MAOBCTSCF10KIF11
SCHEMBL8027622 0.85 GPR84 (0.40) GPR84MAOBCTSCF10RARB
SCHEMBL12999140 0.85 GPR84 (0.40) GPR84MAOBCTSCF10KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7425354-B2 Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element CHISSO CORPORATION (JP) 2008-09-16 US disclosed