Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMCHD1 | A6NHR9 | 1/20 | 0.40 |
| ▸ | MYO1G | B0I1T2 | 1/20 | 0.40 |
| ▸ | AIP | O00170 | 1/20 | 0.40 |
| ▸ | AP3B1 | O00203 | 1/20 | 0.40 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | SAP18 | O00422 | 1/20 | 0.40 |
| ▸ | KPNA3 | O00505 | 1/20 | 0.40 |
| ▸ | PPP6C | O00743 | 1/20 | 0.40 |
| ▸ | TCERG1 | O14776 | 1/20 | 0.40 |
| ▸ | UBE2L6 | O14933 | 1/20 | 0.40 |
| ▸ | PPP1R12A | O14974 | 1/20 | 0.40 |
| ▸ | U2SURP | O15042 | 1/20 | 0.40 |
| ▸ | SETD1A | O15047 | 1/20 | 0.40 |
| ▸ | ARPC1B | O15143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264509 | 0.97 | BRD4 (0.44) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL12172317 | 0.92 | BRD4 (0.41) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL12099215 | 0.90 | BRD4 (0.40) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL2602023 | 0.90 | BRD4 (0.40) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL12099217 | 0.90 | BRD4 (0.40) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL2119771 | 0.88 | BRD4 (0.40) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL2119819 | 0.88 | TSHR (0.39) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL2117122 | 0.88 | ROCK2 (0.42) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL2117354 | 0.88 | TSHR (0.40) | BRD4TP53LMNAMEN1KMT2A | |
| SCHEMBL2262882 | 0.87 | BRD4 (0.39) | BRD4TP53LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112553-A1 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TARGETS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-09-18 | — | — | WO | disclosed |