Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649764 | 0.78 | CNR2 (0.47) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL14381958 | 0.75 | CNR2 (0.56) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649725 | 0.75 | CNR2 (0.71) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649722 | 0.75 | CNR2 (0.52) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4648499 | 0.73 | CNR2 (0.51) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649620 | 0.71 | CNR2 (0.62) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL5213108 | 0.69 | CNR2 (0.69) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL14006020 | 0.67 | CNR2 (0.46) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649692 | 0.67 | CNR2 (0.50) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649694 | 0.67 | CNR2 (0.58) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718613-B1 | PYRIDINE DERIVATIVES AND THEIR USE AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2008-09-03 | — | — | EP | disclosed |