Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 7/20 | 0.38 |
| ▸ | NOS1 | P29475 | 7/20 | 0.38 |
| ▸ | NOS2 | P35228 | 7/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649624 | 0.92 | CNR2 (0.42) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649775 | 0.82 | CNR2 (0.40) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649736 | 0.82 | CDK4 (0.38) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649694 | 0.81 | CNR2 (0.58) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649722 | 0.79 | CNR2 (0.52) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649780 | 0.77 | CNR2 (0.37) | CNR2CYP3A4CYP2D6CHEK1NTRK1 | |
| SCHEMBL4649712 | 0.77 | CNR2 (0.54) | CNR2NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL4649631 | 0.76 | CNR2 (0.56) | CNR2RAB9ACDK5POLB | |
| SCHEMBL4649764 | 0.75 | CNR2 (0.47) | CNR2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4649071 | 0.75 | CNR2 (0.37) | CNR2CYP2C9CYP2C19CYP1A2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718613-B1 | PYRIDINE DERIVATIVES AND THEIR USE AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2008-09-03 | — | — | EP | disclosed |