SCHEMBL14065136

SCHEMBL14065136

CN(C)c1ccc(-c2cccc(-c3ccccn3)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.48
BCR P11274 1/20 0.48
DCTPP1 Q9H773 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MAPT P10636 1/20 0.46
KDM4E B2RXH2 2/20 0.44
SYK P43405 1/20 0.43
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
PNPLA2 Q96AD5 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CYP2A6 P11509 1/20 0.42
ADK P55263 1/20 0.42
HTR1A P08908 1/20 0.41
HTR7 P34969 1/20 0.41
MITF O75030 1/20 0.41
LMNA P02545 1/20 0.41
HIF1A Q16665 1/20 0.41
GRM5 P41594 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21988543 0.90 KDM4E (0.50) ABL1BCRDCTPP1SMN1; SMN2MAPT
SCHEMBL31400293 0.90 KDM4E (0.50) ABL1BCRDCTPP1SMN1; SMN2MAPT
SCHEMBL210344 0.86 DCTPP1 (0.52) ABL1BCRDCTPP1SMN1; SMN2MAPT
SCHEMBL31054349 0.86 DCTPP1 (0.52) ABL1BCRDCTPP1SMN1; SMN2MAPT
SCHEMBL29978861 0.85 DCTPP1 (0.55) ABL1BCRDCTPP1SMN1; SMN2MAPT
SCHEMBL3177903 0.85 DCTPP1 (0.55) ABL1BCRDCTPP1SMN1; SMN2MAPT
SCHEMBL26499340 0.84 KDM4E (0.52) SMN1; SMN2MAPTKDM4ECYP2A6HTR1A
SCHEMBL14425486 0.84 KDM4E (0.52) SMN1; SMN2MAPTKDM4ECYP2A6HTR1A
SCHEMBL21173056 0.84 KDM4E (0.56) SMN1; SMN2MAPTKDM4ECYP2A6HTR1A
SCHEMBL28432843 0.84 GRM5 (0.43) ABL1BCRSMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269711-A Transition metal luminescent complexes and methods of use 香港大学 2020-06-12 CN disclosed
US-7429426-B2 Organometallic compounds for use in electroluminescent devices THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2008-09-30 US disclosed