Sugi Predict

Sugi Predict / Targets / DCTPP1

DCTPP1

dCTP pyrophosphatase 1 · Q9H773 · DCTPP1 on Sugi Atlas →

16,483 patent compounds predicted against DCTPP1, 8,337 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1097831 SCHEMBL1097831 0.43 8/20
SCHEMBL1107857 SCHEMBL1107857 0.43 8/20
SCHEMBL1107854 SCHEMBL1107854 0.49 6/20
SCHEMBL1107874 SCHEMBL1107874 0.49 6/20
SCHEMBL1107887 SCHEMBL1107887 0.42 5/20
SCHEMBL1107894 SCHEMBL1107894 0.42 5/20
SCHEMBL1107848 SCHEMBL1107848 0.40 5/20
SCHEMBL1107883 SCHEMBL1107883 0.40 5/20
SCHEMBL1019999 SCHEMBL1019999 0.37 5/20
SCHEMBL202953 SCHEMBL202953 0.36 5/20
SCHEMBL204557 SCHEMBL204557 0.34 5/20
SCHEMBL317642 SCHEMBL317642 0.70 4/20
SCHEMBL532153 SCHEMBL532153 0.51 4/20
SCHEMBL532154 SCHEMBL532154 0.51 4/20
SCHEMBL435000 SCHEMBL435000 0.47 4/20
SCHEMBL532375 SCHEMBL532375 0.40 4/20
SCHEMBL1029800 SCHEMBL1029800 0.36 4/20
SCHEMBL1171802 SCHEMBL1171802 0.59 3/20
SCHEMBL532633 SCHEMBL532633 0.59 3/20
SCHEMBL532748 SCHEMBL532748 0.58 3/20

Clinical trials — most relevant to DCTPP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Epirubicin, Docetaxel, and Capecitabine in Treating Women With Stage IIIA or Stage IIIB Breast Cancer PHASE2COMPLETED
Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors PHASE1COMPLETED
Exome Sequencing for Atypical Femoral Fractures nanCOMPLETED
Immune Signature of Palmoplantar Pustulosis nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Natural History of GACI With or Without ARHR2 or PXE nanUNKNOWN
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism nanNOT_YET_RECRUITING
A Study Providing Genetic Testing to Find Those Who May Have Primary Ciliary Dyskinesia for Potential Clinical Trials nanACTIVE_NOT_RECRUITING
Diadenosine Polyphosphates and Mucin Associated With Ocular Surface Disorders nanUNKNOWN
Evaluating Face-Recognition Technology in Syndrome Diagnosis nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Studying Phosphorus Metabolism nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
The Congenital Dyserythropoietic Anemia Registry (CDAR) nanRECRUITING
Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of Samples nanCOMPLETED
Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact nanCOMPLETED
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2) nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Pathophysiology of Paget's Disease of Bone nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Phenotype and Etiology of Pallister-Hall Syndrome nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Study of Skeletal Disorders and Short Stature nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a DCTPP1 binder may also engage these)

ProteinNameSimilarity
Q9QY93 — 0.998 Q9QY93 →
Q91VC0 — 0.998 Q91VC0 →
Q32KY6 — 0.997 Q32KY6 →
Q8PLG5 — 0.981 Q8PLG5 →
A5FYE6 — 0.980 A5FYE6 →
Q938W0 — 0.980 Q938W0 →
Q8DM88 — 0.980 Q8DM88 →
Q7U635 — 0.979 Q7U635 →
A1TL08 — 0.978 A1TL08 →
P60539 — 0.978 P60539 →
Q5FTN2 — 0.978 Q5FTN2 →
Q9RWD6 — 0.978 Q9RWD6 →
Q87C35 — 0.977 Q87C35 →
Q9WX15 — 0.977 Q9WX15 →
Q8P9N8 — 0.977 Q8P9N8 →
Q7NLB5 — 0.977 Q7NLB5 →
P74755 — 0.977 P74755 →
Q9PBD1 — 0.976 Q9PBD1 →
P18182 — 0.976 P18182 →
A1WJP5 — 0.976 A1WJP5 →
A9V2C1 — 0.975 A9V2C1 →
Q7MAQ8 — 0.975 Q7MAQ8 →
C5CQK2 — 0.974 C5CQK2 →
A9FDP5 — 0.974 A9FDP5 →
B8IJD1 — 0.974 B8IJD1 →
A1WFS9 — 0.974 A1WFS9 →
Q2J781 — 0.974 Q2J781 →
H1AAP2 — 0.974 H1AAP2 →
O87833 — 0.973 O87833 →
A9G7Z8 — 0.973 A9G7Z8 →