Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579475 | 0.94 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9099692 | 0.94 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9642504 | 0.94 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL11015972 | 0.94 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL1132359 | 0.94 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7804219 | 0.94 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL27275320 | 0.94 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9699338 | 0.91 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL11690600 | 0.91 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL11690596 | 0.91 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427680-B2 | Fluorogenic substrates for BETA-lactamase gene expression | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-23 | — | — | US | disclosed |