Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24231232 | 0.86 | — | — | |
| SCHEMBL31374746 | 0.86 | TDP1 (0.41) | TDP1CYP1A2CYP2D6 | |
| SCHEMBL1429706 | 0.77 | TDP1 (0.53) | TDP1 | |
| SCHEMBL11131387 | 0.76 | PLA2G1B (0.32) | PLA2G1BPLA2G2A | |
| SCHEMBL13741824 | 0.75 | CACNA2D1 (0.35) | TDP1CACNA2D1 | |
| SCHEMBL27798996 | 0.75 | TDP1 (0.50) | TDP1 | |
| SCHEMBL6142352 | 0.74 | SIGMAR1 (0.35) | PLA2G1BPLA2G2A | |
| SCHEMBL6168753 | 0.74 | PLA2G1B (0.35) | PLA2G1BPLA2G2A | |
| SCHEMBL19397732 | 0.72 | TDP1 (0.39) | TDP1CYP1A2CYP2D6 | |
| SCHEMBL19397723 | 0.72 | TDP1 (0.39) | TDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419990-B2 | Piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-7419990-B2 | Piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-09-02 | — | — | US | disclosed |