Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065624 | 0.86 | SLC22A1 (0.35) | ALDH1A1TDP1SIGMAR1 | |
| SCHEMBL12085574 | 0.82 | PAOX (0.40) | PAOXALDH1A1GAAAPAF1NPC1 | |
| SCHEMBL152809 | 0.82 | PAOX (0.40) | PAOXALDH1A1GAAAPAF1NPC1 | |
| SCHEMBL19456546 | 0.82 | PAOX (0.42) | PAOXALDH1A1GAAKDM4EAPAF1 | |
| SCHEMBL2196628 | 0.82 | PAOX (0.35) | PAOXALDH1A1GAAAPAF1NPC1 | |
| SCHEMBL23468502 | 0.80 | PAOX (0.39) | PAOXALDH1A1GAAHTTAPAF1 | |
| SCHEMBL2155764 | 0.80 | TDP1 (0.40) | PAOXALDH1A1KDM4EHTTPOLB | |
| SCHEMBL11465053 | 0.78 | PAOX (0.42) | PAOXALDH1A1GAAHTTAPAF1 | |
| SCHEMBL9419674 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EHTTPOLBTDP1 | |
| SCHEMBL30891548 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419990-B2 | Piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-7419990-B2 | Piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-09-02 | — | — | US | disclosed |