Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066661 | 0.98 | TP53 (0.52) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL14066646 | 0.91 | TP53 (0.40) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL14066642 | 0.90 | TP53 (0.53) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL14066635 | 0.90 | TP53 (0.53) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL4652321 | 0.88 | TP53 (0.54) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL14066639 | 0.88 | TP53 (0.54) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL14066663 | 0.88 | TP53 (0.54) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL4652289 | 0.88 | TP53 (0.54) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL4652316 | 0.87 | TP53 (0.52) | TP53MDM2BCL2L1MCL1BCL2L11 | |
| SCHEMBL4651217 | 0.87 | BCL2L1 (0.58) | TP53MDM2BCL2L1MCL1BCL2L11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408986-B1 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2008-09-24 | — | — | EP | disclosed |