Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.87 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.70 |
| ▸ | RXRA | P19793 | 1/20 | 0.65 |
| ▸ | RXRB | P28702 | 1/20 | 0.65 |
| ▸ | RXRG | P48443 | 1/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.62 |
| ▸ | MMP12 | P39900 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533619 | 1.00 | FFAR1 (0.87) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL8618654 | 0.93 | FFAR1 (1.00) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL1211561 | 0.93 | FFAR1 (1.00) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL69746 | 0.92 | FFAR1 (0.81) | FFAR1KEAP1FFAR4CA1CA2 | |
| Hydrochloric Acid SCHEMBL5753893 | 0.91 | FFAR1 (0.96) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL3293457 | 0.91 | FFAR1 (0.74) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL7630944 | 0.91 | FFAR1 (0.96) | FFAR1KEAP1RXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL25264643 | 0.90 | FFAR1 (0.77) | FFAR1KEAP1FFAR4CA1CA2 | |
| SCHEMBL8339608 | 0.89 | FFAR1 (0.71) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL23512465 | 0.89 | FFAR1 (0.71) | FFAR1KEAP1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408986-B1 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2008-09-24 | — | — | EP | disclosed |