Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.71 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73828 | 0.94 | FFAR1 (0.65) | FFAR1KEAP1CA1CA2FFAR4 | |
| Hydrochloric Acid SCHEMBL3128046 | 0.92 | FFAR1 (0.63) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL27544320 | 0.92 | FFAR1 (0.63) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL14066660 | 0.89 | FFAR1 (0.87) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL3533619 | 0.89 | FFAR1 (0.87) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL11760587 | 0.89 | SMN1; SMN2 (0.60) | FFAR1RXRARXRBRXRGMMP12 | |
| SCHEMBL8618654 | 0.83 | FFAR1 (1.00) | FFAR1KEAP1RXRARXRBRXRG | |
| SCHEMBL1211561 | 0.83 | FFAR1 (1.00) | FFAR1KEAP1RXRARXRBRXRG | |
| Benzidine SCHEMBL28841695 | 0.83 | CYP3A4 (0.52) | FFAR1CA1CA2 | |
| Benzidine SCHEMBL28008037 | 0.83 | CYP3A4 (0.52) | FFAR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |