Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763711 | 0.89 | PKM (0.74) | FABP6SMN1; SMN2PKMMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL1596692 | 0.87 | PKM (0.72) | FABP6SMN1; SMN2PKMMAPK1KDM4E | |
| SCHEMBL28121975 | 0.87 | FABP6 (0.67) | FABP6SMN1; SMN2PKMMAPK1KDM4E | |
| SCHEMBL31329773 | 0.87 | FABP6 (0.67) | FABP6SMN1; SMN2PKMMAPK1KDM4E | |
| SCHEMBL18029395 | 0.84 | KDM4E (0.65) | FABP6SMN1; SMN2PKMMAPK1KDM4E | |
| SCHEMBL3323247 | 0.84 | FABP6 (0.60) | FABP6SMN1; SMN2PKMMAPK1KDM4E | |
| SCHEMBL3323252 | 0.84 | KDM4E (0.65) | FABP6SMN1; SMN2PKMMAPK1KDM4E | |
| SCHEMBL13149228 | 0.83 | CHRM2 (0.80) | FABP6SMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL29457007 | 0.82 | PKM (0.66) | PKMMAPK1ALDH1A1POLBMEN1 | |
| SCHEMBL22702163 | 0.82 | PKM (0.66) | FABP6PKMMAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |