Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545481 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1PKMBCHEMEN1 | |
| Bromide SCHEMBL10773361 | 0.81 | BCHE (0.61) | KDM4EALDH1A1PKMBCHEMEN1 | |
| SCHEMBL1289738 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1PKMBCHEMEN1 | |
| SCHEMBL14590482 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1PKMBCHELMNA | |
| SCHEMBL30442024 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1PKMBCHEMEN1 | |
| Hydrochloric Acid SCHEMBL25336473 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1PKMBCHEMEN1 | |
| Hydrochloric Acid SCHEMBL1289689 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1PKMBCHEMEN1 | |
| SCHEMBL12992413 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1PKMBCHEMEN1 | |
| SCHEMBL14626029 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1PKMBCHEMEN1 | |
| SCHEMBL12026449 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1PKMBCHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |