Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 14/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067229 | 0.87 | NAMPT (0.56) | HPGDALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL7285536 | 0.82 | NOTUM (0.60) | HPGDNOTUM | |
| SCHEMBL4235087 | 0.80 | MEN1 (0.57) | HPGDTSHRALDH1A1 | |
| SCHEMBL7277193 | 0.80 | NOTUM (0.58) | ALDH1A1NOTUMCYP2C19 | |
| SCHEMBL14626151 | 0.80 | HPGD (0.51) | HPGDTSHRALDH1A1KDM1APLA2G7 | |
| SCHEMBL8476735 | 0.79 | F10 (0.56) | HPGDTSHRALDH1A1KDM1A | |
| SCHEMBL14590639 | 0.79 | HSD17B3 (0.57) | TSHRALDH1A1NOTUMKDM1A | |
| SCHEMBL12853762 | 0.78 | KMT2A (0.62) | HPGDTSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19954060 | 0.77 | KMT2A (0.57) | HPGDTSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2814463 | 0.77 | KMT2A (0.57) | HPGDTSHRALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |