Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 14/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067262 | 0.80 | HPGD (0.55) | HPGDALDH1A1KDM1APLA2G7TSHR | |
| SCHEMBL13236584 | 0.79 | ALDH1A1 (0.50) | ALDH1A1AKR1C1MAPK1KDM1AGAA | |
| SCHEMBL14625863 | 0.78 | HSD17B3 (0.50) | ALDH1A1AKR1C1KDM1AL3MBTL1POLB | |
| SCHEMBL8476735 | 0.75 | F10 (0.56) | HPGDALDH1A1KDM1AGAAL3MBTL1 | |
| SCHEMBL7844114 | 0.74 | ALDH1A1 (0.62) | ALDH1A1AKR1C1MAPK1KDM1APOLB | |
| SCHEMBL14626051 | 0.74 | AKR1C3 (0.42) | HPGDALDH1A1 | |
| SCHEMBL4235087 | 0.73 | MEN1 (0.57) | HPGDALDH1A1MAPK1TSHR | |
| SCHEMBL12853762 | 0.73 | KMT2A (0.62) | HPGDALDH1A1MAPK1POLBTSHR | |
| Hydrochloric Acid SCHEMBL4237529 | 0.72 | HPGD (0.55) | HPGDALDH1A1MAPK1KDM1APLA2G7 | |
| SCHEMBL10721733 | 0.72 | HPGD (0.95) | HPGDALDH1A1MAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |