Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921574 | 0.88 | HRH3 (0.70) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL23053146 | 0.86 | CYP1A2 (0.69) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| Hydrochloric Acid SCHEMBL6894630 | 0.85 | ALDH1A1 (0.61) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL6890029 | 0.84 | CHRM2 (0.57) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL1392847 | 0.82 | CHRM2 (0.70) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL18160871 | 0.82 | DPP7 (0.57) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL3398272 | 0.81 | DPP7 (0.56) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL746674 | 0.81 | CYP1A2 (0.67) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL27379291 | 0.81 | CYP1A2 (0.62) | CYP1A2ALDH1A1CYP2C19HRH3LMNA | |
| SCHEMBL14824935 | 0.80 | CYP1A2 (0.67) | CYP1A2ALDH1A1CYP2C19HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |