Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781973 | 0.89 | SETDB1 (0.51) | SETDB1MTNR1AMTNR1BNPSR1CYP2D6 | |
| SCHEMBL14204990 | 0.87 | SETDB1 (0.59) | SETDB1MTNR1AMTNR1BNPSR1NQO2 | |
| SCHEMBL21051098 | 0.86 | HTT (0.50) | SETDB1MTNR1AMTNR1BNPSR1CYP2D6 | |
| SCHEMBL29675775 | 0.83 | SETDB1 (0.53) | SETDB1MTNR1AMTNR1BNPSR1NQO2 | |
| SCHEMBL15030741 | 0.81 | SETDB1 (0.51) | SETDB1MTNR1AMTNR1BNPSR1NQO2 | |
| SCHEMBL14651452 | 0.81 | SETDB1 (0.54) | SETDB1MTNR1AMTNR1BNPSR1NQO2 | |
| SCHEMBL10781979 | 0.79 | SETDB1 (0.49) | SETDB1MTNR1AMTNR1BNPSR1NQO2 | |
| SCHEMBL1607140 | 0.78 | TDP1 (0.43) | — | |
| SCHEMBL29681348 | 0.78 | TDP1 (0.43) | — | |
| SCHEMBL29681353 | 0.78 | TDP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |